E-ISSN 2636-865X
Research Article
Effects of Obesity on Migraine in Women
1 Gaziosmanpaşa Üniversitesi Tıp Fakültesi, Nöroloji, Tokat, Türkiye  
Neurol Sci Neurophysiol 2006; 23: 295-302

Key Words: Migraine, obesity, BMI body mass index, hypothalamus
Abstract

Introduction: With a rapidly increasing prevalence worldwide in recent decades, obesity has started to be an important public health issue in all developed countries. There are few studies focusing on the relationship of obesity with migraine. We intended to study clinical features of migraine in obes women, frequency of attacks, severity and duration of pain, use of prophylactic drugs for migraine,, use of analgesics in attacks and the effects of migraine on daily lives.

 

Material and Methods: In this prospective study, 84 women patients with migraine were classified as group I for those with a body mass index of 30 and over, and group II for those with a body mass index of 25 and less. Groups were compared in socio demographical features, clinical properties, frequency and severity of migraine attacks, prophylactic drugs used for treatment, analgesics used in such attacks and the effects of pain on daily life.

 

Results: It has been found that migraine attacks were significantly earlier in women with obesity. In this group, frequency and severity of migraine attacks, prophylactic drugs used for treatment, analgesics used in such attacks, and restriction of daily activities due to pain differed significantly compared to the group with no obesity.

 

Conclusions: Obesity might be triggering migraine attacks in women thru endogenous mechanisms dependant upon hypothalamic dysfunction and thru exogenous mechanisms dependant upon excess food intake.

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