E-ISSN 2636-865X
Research Article
Sex Hormone Levels During and Between Attacks At Female Migraine Patients
1 Haydarpaşa Numune Eğitim ve Araştırma Hastanesi, Nöroloji, İstanbul, Türkiye  
Neurol Sci Neurophysiol 2008; 25: 84-91

Key Words: Migraine,attacks, sex hormones
Abstract

Background: The objective of our study is to investigate the relation between the serum levels of sex hormones and migraine headache in female migraine patients. Serum levels of estrogen, progesterone, follicle stimulating hormone, luteinizing hormone and prolactine were measured during the headache attack and in the interval period in female migraine patients with or without aura.

 

Materials and Methods: 46 female migraine patients who had no systemic disease were enrolled in this study. The patients ranging in age from 15 to 45 years. Blood samples were taken from the patients during the headache attack and in the interval period. We measured the serum level of estrogen, progesterone, follicle stimulating hormone, luteinizing hormone and prolactine.

 

Results: The serum level of estrogen during the headache attack were significantly lower than the interval period level (absolute value; t>1.96). There were no differences in all other sex hormones levels between headache attack and interval period (absolute value; t<1.96).

 

Conclusion: The serum level of estrogen during the headache attack were significantly lower than the serum level of interval period. However no differences were found in all other sex hormones levels between headache attack and interval period. It was described that significant variations occur in the serum levels of sex hormones during headache attack or in the interval period in female migraine patients. The examination of serum sex hormones levels can be useful to determine the etiopathogenesis and treatment in female migraine patients.

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