E-ISSN 2636-865X
Research Article
The Relationship Between Tension-Type Headache Patients With Anemia and Restless-leg Syndrome
1 Haydarpaşa Numune Eğitim ve Araştırma Hastanesi, Nöroloji, İstanbul, Türkiye  
2 Özel Yaşam Hastanesi, Nöroloji, Tekirdağ, Türkiye  
Neurol Sci Neurophysiol 2009; 26: 305-310

Key Words: Tension-type headache, anemia, restless-leg syndrome

Objective: The aim of the study was to investigate the prevalence of restless-leg syndrome (RLS), widespread of the RLS symptoms, effect of sypmtoms and applied therapies in tension-type headache patients with anemia due to iron deficiency and vitamin B12 deficiency. We also examined the effects of ferritin in RLS.


Material and methods: We evaluated 56 tension-type headache patients from our headache clinic. In the patient group; 32 patients had iron deficiency, 24 patients had megaloblastic anemia caused by vitamin B12 deficiency. 20 control subjects with tension-type headache were included to the study. Control group subjects did not have anemia. Control and patient group were evaluated according to RLS diagnostic criteria.


Results: The prevalence fo RLS was 12.5% in iron deficiency anemia, 8.03% in megaloblastic anemia, 5% in control group, respectively. The incidence of RLS was 7.7% in all patient and control group.


Conclusion: RLS is especially seen in female and older age. The alterations in iron metabolism can be a facilitating factor for appearing of RLS

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