E-ISSN 2636-865X
Research Article
Headache frequency and its relation with disease activity in patients with Behçet’s disease: a case-control study
1 Department of Neurology, Süleyman Demirel University, School of Medicine, Isparta, Turkey  
2 Department of Dermatology, Süleyman Demirel University, School of Medicine, Isparta, Turkey  
3 Department of Psychiatry, Süleyman Demirel University, School of Medicine, Isparta, Turkey  
4 Clinic of Neurology, Eğirdir Public Hospital, Isparta, Turkey  
Neurol Sci Neurophysiol 2019; 36: 98-103
DOI: 10.5152/NSN.2019.10911
Key Words: Behçet’s disease, headache, migraine
Abstract

 

Objective: The frequency of neurologic manifestations of Behçet disease (BD) is between 5% and 30%. The most common neurologic symptoms of BD are headache, which may be due to migraine, tension-type headache (TTH), uveitis or a direct consequence of neuro-Behçet disease. We aimed to evaluate the frequency of headache and the frequency of different headache types in patients with BD with or without neurologic involvement.

 

Methods: One hundred two patients (44 males, 58 females) who fulfilled the International Study Group for BD classification criteria were included in the study. The control group consisted of 115 healthy subjects (41 males, 74 females) who were an age and sex-matched population. The patients were interviewed to determine a history of BD and headache.

 

Results: There was no significant difference between the patients and controls in terms of the presence of headache. The majority of the headaches of patients with BD were migraine and TTH. In the BD group, the mean activity score was higher in the headache group than in the headache-free group. In the subgroups, the mean BD activity score was 4.6±1.9 in patients with migraine and the mean BD activity score was 3.0±1.6 in patients with TTH. There was a significant difference between the migraine and TTH group in terms of BD activity. 

 

Conclusion: Migraine and TTH were the most common types of headache in both the patients with BD and the control group. The activity score of the disease was found to be higher in patients with Behçet's headache. In conclusion, physicians should be aware that worsening headache may be related to disease exacerbation in patients with BD.

 

 

You may cite this article as: Yürekli VA, Erturan İ, Şengeze N, Atay İM, Gürler S. Headache frequency and its relation with disease activity in patients with Behçet’s disease:  a case-control study. Neurol Sci Neurophysiol 2019; 36(2): 98-103.

Key Words
Authors
All
Author's Corner
Survey
AVES | Copyright © 2019 Latest Update: 03.09.2019