Neurological Sciences and Neurophysiology
Research Article

Prognostic Factors in Metastatic Brain Tumors: Study of 62 Patients

1.

Celal Bayar Universty School of Medicine, Neurosurgery, Manisa, Türkiye

2.

Celal Bayar University School of Medicine, Neurosurgery, Manisa, Türkiye

3.

Izmir Ataturk Training and Research Hospital , Radiation Oncology, İzmir, Türkiye

Neurol Sci Neurophysiol 2012; 29: 732-743
Read: 36 Downloads: 8 Published: 03 September 2019

Abstract

Background: Brain metastases are the major cause of morbidity and mortality in patients with cancer. Variety of clinical and autopsy studies showed that brain metastases develop at 15%-45% of all cancer patients during the course of the disease and 1/2-2/3 of them were symptomatic. Average life expectancy of cancer patients with untreated metastatic brain tumors are approximately 1-2 months.

 

Methods: We investigated the prognostic factors of removal of metastatic brain tumors in patients who admitted to neurosurgery department. Eighteen of 80 patients in the program excluded for various reasons and this study was completed with the remaining 62 cases.

 

Results: Our study showed that neurological and general status, the extension of surgical resection, presence of the extra-cranial metastases at diagnosis and localization of the primary focus affect the prognosis.

 

Conclusion: In the planning of treatment of patients with metastatic brain tumors, colleagues have to keep in mind level of neurological and general status, the extension of surgical resection, presence of the extra-cranial metastases at diagnosis and localization of the primary focus affect the prognosis. Surgical resection is beneficial for improving neurological status and survival of patients in brain metastases. Local control is essential and can be achieved with one of the adjunct therapies following the surgery.

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EISSN 2636-865X