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Year : 2020  |  Volume : 37  |  Issue : 4  |  Page : 155-163

Neuroinflammation in Alzheimer's disease continuum

1 Department of Neurology, Faculty of Medicine, TOBB ETU, Ankara, Turkey
2 Institute of Neurological Sciences and Psychiatry; Department of Neurology, Faculty of Medicine, Hacettepe University; Neuroscience and Neurotechnology Center of Excellence (NÖROM), Ankara, Turkey

Correspondence Address:
Aslihan Taskiran-Sag
Department of Neurology, Faculty of Medicine, TOBB ETU, Ankara
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/nsn.nsn_190_20

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Aging population brings an ever-increasing global burden of dementia, and Alzheimer's disease (AD) is the most frequent type worldwide. Many years of research have introduced characteristic cerebral histopathological and molecular changes in this disease. However, all attempts to establish an effective treatment have failed. In this review, we aim to address the basic evidence regarding the role of inflammatory mediators in AD and their link to the other pathogenetic pathways. Novel findings based on advanced biotechnology and bioinformatics are covered briefly, as well.

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