E-ISSN 2636-865X
Research Article
Demographic characteristics of patients who recovered or worsened after intravenous thrombolysis within 24 hours of acute ischemic stroke
1 Department of Neurology, Gaziantep University School of Medicine, Gaziantep, Turkey  
2 Department of Neurology, Başkent University Adana Application Hospital, Adana, Turkey  
3 Department of Neurology Kahraman Maraş Sütçüimam University School of Medicine, Kahramanmaraş, Turkey  
Neurol Sci Neurophysiol 2018; 35: 29-33
DOI: 10.5152/NSN.2018.10021
Key Words: Acute ischemic stroke, recover, worsening
Abstract

 

Objective: The aim of this study was to evaluate the demographics of patients who experienced recovery or worsening after receiving intravenous thrombolytic treatment within 24 hours of the onset of acute ischemic stroke (AIS).

 

Methods: This retrospective study included patients with AIS who were admitted to emergency units within 4.5 hours of AIS between January 2012 and December 2015. Recovery was defined as a decrease of ≥4 points in the National Institutes of Health Stroke Scale (NIHSS) score within 24 hours (group I), and worsening was defined as an increase of ≥4 points in NIHSS score within 24 hours compared with admission (group II).

 

Results: The study included a total of 86 patients comprising 55.8% males, with a mean (±SD) age of 61.1 (±13.1) years. The mean patient age was similar in both sexes. Of the total 86 patients, 80.2% experienced recovery within 24 hours (group I) and symptoms worsened in 19.8% (group II). No significant sex or age difference was determined in terms of recovery. Patients receiving thrombolysis within 1-3 hours had a higher recovery ratio compared with patients who received treatment within 3-4.5 hours. Patients without diabetes mellitus had a better recovery ratio compared with those with diabetes mellitus.

 

Conclusion: A relatively high recovery rate was determined at 24 hours after thrombolysis in patients with AIS. Demographic characteristics were not determined to be contributing factors to this outcome, but the time to thrombolytic treatment and having diabetes mellitus were observed to be more significant predictors of patient recovery.

 

You may cite this article as: İnanç Y, Arlıer Z, Giray S, İnanç Y. Demographic characteristics of patients who recovered or worsened after intravenous thrombolysis within 24 hours of acute ischemic stroke. Neurol Sci Neurophysiol 2018; 35: 29-33.

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